The endothelium is composed of a monolayer of cells which lines the inner side of blood vessels, in direct contact with the circulation. Endothelial cells play essential roles in the regulation of vascular dilation, thrombosis, and the immune response, and are the main cellular actors of angiogenesis, the process by which new blood vessels arise from the established vascular network.

activation

     We study the endogenous molecular mechanisms involved in maintaining endothelial cells non-activated and their roles in tumor escape from immunity.

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